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Juan Pablo de Rivero Vaccari Selected Research

Inflammasomes

1/2021Tumor necrosis factor-alpha and interferon-gamma induce inflammasome-mediated corneal endothelial cell death.
1/2021Enoxaparin Attenuates Acute Lung Injury and Inflammasome Activation after Traumatic Brain Injury.
1/2021Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats.
12/2020Inflammasome Proteins as Inflammatory Biomarkers of Age-Related Macular Degeneration.
11/2020ASC, IL-18 and Galectin-3 as Biomarkers of Non-Alcoholic Steatohepatitis: A Proof of Concept Study.
9/2020Role of inflammasomes in multiple sclerosis and their potential as therapeutic targets.
6/2020The Inflammasome Adaptor Protein ASC in Mild Cognitive Impairment and Alzheimer's Disease.
5/2020IC100: a novel anti-ASC monoclonal antibody improves functional outcomes in an animal model of multiple sclerosis.
5/2020Levels of caspase-1 in cerebrospinal fluid of patients with traumatic brain injury: correlation with intracranial pressure and outcome.
1/2020Neural-respiratory inflammasome axis in traumatic brain injury.
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Juan Pablo de Rivero Vaccari Research Topics

Disease

22Inflammation (Inflammations)
05/2022 - 10/2006
15Traumatic Brain Injuries (Traumatic Brain Injury)
05/2022 - 10/2006
10Spinal Cord Injuries (Spinal Cord Injury)
02/2019 - 03/2008
8Stroke (Strokes)
10/2022 - 03/2009
5Multiple Sclerosis
09/2020 - 01/2016
5Wounds and Injuries (Trauma)
01/2016 - 03/2008
4Lung Injury
01/2021 - 01/2017
4Cognitive Dysfunction
06/2020 - 12/2011
4Brain Injuries (Brain Injury)
01/2019 - 07/2011
4Brain Ischemia (Cerebral Ischemia)
01/2019 - 03/2009
4Ischemia
04/2018 - 03/2009
3Disease Progression
12/2020 - 01/2018
3Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
05/2020 - 01/2016
3Infections
01/2020 - 05/2014
3Neuroinflammatory Diseases
01/2016 - 04/2014
3Porcine Reproductive and Respiratory Syndrome (PRRS)
08/2014 - 07/2013
2Acute Lung Injury
01/2021 - 01/2018
2Alzheimer Disease (Alzheimer's Disease)
06/2020 - 04/2014
2Hyperoxia
01/2019 - 01/2017
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 02/2012
2Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
04/2018 - 01/2015
2Intervertebral Disc Degeneration
11/2016 - 01/2016
2Melanoma (Melanoma, Malignant)
04/2014 - 03/2012
2Hypothermia
10/2012 - 10/2006
2Contusions
03/2012 - 07/2009
1Ischemic Stroke
10/2022
1Diabetic Nephropathies (Diabetic Nephropathy)
01/2022
1Lupus Nephritis
01/2022
1Macular Degeneration (Age-Related Maculopathy)
12/2020
1Liver Diseases (Liver Disease)
11/2020
1Alcoholic Fatty Liver
11/2020
1Female Infertility
01/2020
1Pre-Eclampsia (Preeclampsia)
01/2020
1COVID-19
01/2020
1Psoriasis (Pustulosis Palmaris et Plantaris)
01/2020
1Infertility (Sterility)
01/2020
1Disseminated Intravascular Coagulation
01/2020
1Endometriosis
01/2020
1Psoriatic Arthritis
01/2020
1Central Nervous System Diseases (CNS Diseases)
01/2020
1Ventilator-Induced Lung Injury
01/2020
1Infarction (Infarctions)
04/2018
1Vascular Remodeling
01/2017
1Bronchopulmonary Dysplasia
01/2017
1Obesity
11/2016
1Chronic Renal Insufficiency
11/2016
1Encephalomyelitis (Myeloencephalitis)
05/2014

Drug/Important Bio-Agent (IBA)

42InflammasomesIBA
01/2021 - 03/2008
20Proteins (Proteins, Gene)FDA Link
05/2022 - 10/2006
12CytokinesIBA
10/2022 - 03/2008
9Biomarkers (Surrogate Marker)IBA
10/2022 - 01/2018
9InterleukinsIBA
01/2021 - 03/2009
7Interleukin-18 (Interleukin 18)IBA
11/2020 - 03/2009
3CaspasesIBA
01/2022 - 10/2006
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020 - 10/2006
3Type I Tumor Necrosis Factor ReceptorsIBA
01/2020 - 10/2006
3NLR ProteinsIBA
01/2016 - 07/2013
3Pattern Recognition ReceptorsIBA
08/2014 - 07/2013
2Interleukin-6 (Interleukin 6)IBA
10/2022 - 01/2020
2Caspase 1 (ICE Protease)IBA
01/2022 - 01/2016
2Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
01/2021 - 01/2020
2Enoxaparin (Lovenox)FDA LinkGeneric
01/2021 - 01/2020
2Monoclonal AntibodiesIBA
05/2020 - 01/2020
2Estrogen Receptor betaIBA
04/2018 - 02/2016
2salicylhydroxamic acid (SHAM)IBA
01/2018 - 07/2011
2Interleukin-1 (Interleukin 1)IBA
01/2016 - 08/2011
2NucleotidesIBA
01/2016 - 12/2011
2Tretinoin (Retinoic Acid)FDA LinkGeneric
01/2015 - 03/2012
2DNA (Deoxyribonucleic Acid)IBA
04/2014 - 03/2014
2Adenosine Triphosphate (ATP)IBA
03/2014 - 07/2013
2Interleukin-1beta (Interleukin 1 beta)IBA
07/2009 - 03/2008
2Neutralizing AntibodiesIBA
07/2009 - 03/2009
2X-Linked Inhibitor of Apoptosis ProteinIBA
07/2009 - 10/2006
1Interleukin-13IBA
10/2022
1Interleukin-2 (IL2)IBA
10/2022
1Vascular Endothelial Growth Factor CIBA
10/2022
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2022
1Interleukin-4 (Interleukin 4)IBA
10/2022
1Interleukin-8 (Interleukin 8)IBA
10/2022
1Interleukin-16 (Interleukin 16)IBA
10/2022
1Galectin 3 (LGALS3)IBA
11/2020
1Dacarbazine (DIC)FDA LinkGeneric
01/2020
1Type II Tumor Necrosis Factor ReceptorsIBA
01/2020
1Carbon MonoxideIBA
02/2019
1interleukin-1beta-converting enzyme inhibitorIBA
01/2019
1N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketoneIBA
01/2019
1Estrogens (Estrogen)FDA Link
01/2019
1erucylphosphocholineIBA
01/2019
1SolutionsIBA
01/2019
1NicotineFDA Link
04/2018
1Saline SolutionIBA
01/2017
1NSC 23766IBA
01/2017
1Insulin-Like Growth Factor I (IGF-1)IBA
11/2016
1Multiprotein ComplexesIBA
01/2016
1Pathogen-Associated Molecular Pattern MoleculesIBA
08/2014
1Toll-Like Receptors (Toll-Like Receptor)IBA
08/2014
1C-Type Lectins (C-Type Lectin)IBA
08/2014

Therapy/Procedure

5Therapeutics
01/2020 - 01/2016
2Intraperitoneal Injections
01/2019 - 01/2017
1Artificial Respiration (Mechanical Ventilation)
01/2020